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Genome + CellsGene Editing, Gene Therapy, and RNA Medicines: Three Different Ways to Change an Outcome
In December 2023 the FDA approved Casgevy, the first CRISPR-based therapy, for sickle cell disease. Here is how gene editing, gene therapy and RNA medicines differ, and what that approval does and doesn't prove.
BreakthroughsInside a Clinical Trial: What Phase 1, 2, and 3 Results Really Mean
A positive Phase 1 result and a positive Phase 3 result sound similar but mean very different things. Here is what each stage of a clinical trial is designed to show, and what it cannot.
Companies + StocksThe Biotech Startup Map: How Young Companies Move From Discovery to Patients
Many biotech startups spend years building evidence rather than selling products. This map traces the stations most pass through, from licensing a discovery to the forks where companies partner, sell, go public or stop.
BreakthroughsThe Breakthrough Reality Check: Seven Questions to Ask Before Sharing a Medical Headline
Health headlines often overstate early findings, sometimes before a journalist ever sees them. These seven questions help anyone judge a medical claim in about two minutes before sharing it.