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Vertex Pharmaceuticals
Nasdaq: VRTXVertex develops small-molecule and genetic medicines for serious diseases and is best known for its cystic fibrosis drugs. It co-developed Casgevy, the…
Moderna
Nasdaq: MRNAModerna develops mRNA medicines and markets vaccines against COVID-19 and RSV. With Merck, it is developing intismeran autogene, an individualized neoantigen mRNA…
Illumina
Nasdaq: ILMNIllumina makes DNA sequencing instruments, reagents and software used widely in research and clinical genomics. It acquired GRAIL in 2021 and separated…
Genome + CellsDecode the Genome: What Sequencing Can Tell Us—and What It Cannot
From the $3 billion Human Genome Project to routine sequencing, reading DNA has become easy. Here is what a genome can reveal today, and where uncertain variants, risk scores and missing context set hard limits.
Genome + CellsGene Editing, Gene Therapy, and RNA Medicines: Three Different Ways to Change an Outcome
In December 2023 the FDA approved Casgevy, the first CRISPR-based therapy, for sickle cell disease. Here is how gene editing, gene therapy and RNA medicines differ, and what that approval does and doesn't prove.
DeepTech + MedTechBioprinting Human Tissue: What Works in the Lab, and What Would It Take to Reach Patients?
No bioprinted solid organ has been transplanted into a person, but bioprinting has produced striking lab and animal results. Here is what works today, what has reached early human testing, and what still stands in the way.